Improving antibiotics regimen for MAC lung infections

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Improving antibiotics regimen for MAC lung infections
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MAC bacteria is in the water and soil around us. It doesn't affect most people, but causes slow-growing lung infections in some people. Two clinical trials at Temple Health aim to improve the long-term antibiotic treatment needed to stop MAC.

MAC bacteria is in the water and soil around us. Two Temple Health clinical trials aim to improve the long-term treatment needed to stop MAC.However, when a bacteria commonly found in soil and water gets into our lungs, it can cause trouble, in the form of a MAC infection.But three years ago, he noticed something different.

"Walking up the stairs, getting more short of breath. The cough was there," recalls Tepper, who is also a physician."He looked at it and said - You know, I think you have a touch of MAC," he says."It's pretty much everywhere, especially in soil and water," says Dr. Daniel Salerno, a Temple Health pulmonologist.But people like Tepper with lung problems, or those with weak immune systems, can develop a lung infection."Sometimes the symptoms are subtle.

In addition to shortness of breath and a chronic cough, MAC can cause chest pain or discomfort, a low-grade fever, chronic fatigue, or unexplained weight loss."The standard of care is to treat with three oral antibiotics for months, sometimes up to a year, sometimes up to two years," he says.Tepper developed a fever and stomach issues before finding the right mix.One compares two antibiotics to the standard three drugs, while the other tests a new antibiotic taken alone.

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