⭐ Research Highlight: A mouse study published in NatureCancer suggests that checkpoint inhibitors could negatively impact female fertility, highlighting a major clinical research gap in the cancer immunotherapy field.
It is well known that traditional cancer chemotherapies have lasting effects on female fertility.
Immune-checkpoint inhibitors are now approved for the treatment of numerous types of cancer, many of which occur in women of childbearing age. Despite this, the reproductive toxicity of ICIs has not been formally assessed and clinical trials of these agents have generally not included fertility endpoints.
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