It's all in the DNA. 🧬 engineering
Famous cases of human chimeras have helped us understand a little bit more about this genetic condition. But unfortunately, chimerism has caused trouble in these people’s lives. In 2002, news outlets reported the story of Karen Keegan. When she needed a kidney transplant, she and her family underwent genetic testing to see if any of her family members could donate a kidney to her. But the results showed that, genetically, she could not be the mother of two of her three children.
She was accused of claiming benefits for other people's children and being part of a surrogacy scam. But when her defense attorney Alan Tindell read about Karen Keegan’s case, he asked for Lydia’s genome to be studied more deeply. This way, it was discovered that the DNA of Lydia’s hair and skin did not show her related to her children’s, but DNA taken from a cervical smear did. The conclusion was that she was a human chimera with two different sets of DNA.
She also has sensitivities to food, jewelry, and insect bites and she says she reacts differently on the left side of her body. because —as he later found out— he had two sets of DNA. The DNA extracted from his cheek swab sample didn’t match the DNA in his sperm sample. The man had absorbed his unborn twin brother’s genes in the womb. Genetically, he was his son’s uncle.
It’s important to reiterate that chimerism usually does not exhibit any symptoms and if it does, most people and even doctors do not directly relate the actual symptoms to chimerism when they observe them. Because of this, most human chimeras do not know they’re chimeras until they have to take a DNA test for another reason. This is probably why there are only about 100 registered cases of human chimeras. suggests that there might be many more human chimeras that we will ever know about. Multiple-fetus pregnancies are not so rare, either. Some studies have found that for every eight single-child births, at least one baby comes from a pregnancy that was originally multiple.
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