Efforts to create new antibiotics face significant hurdles: a Colorado senator’s bill to give drug companies incentives has stalled, and a different type of treatment being researched in Boul…
would allow the government to guarantee between $750 million and $3 billion to companies that produce new FDA-approved treatments for the top threats. The payment size would depend on how novel the treatment is, and the money would be spread out over five to 10 years. Any purchases by federal agencies, like Medicare, would be deducted from the subscription amount so the government doesn’t pay twice. States and private health facilities would order and pay as they normally do.
Chatterjee’s lab in Boulder is working on a nanoparticle to try to keep existing antibiotics working a little longer. Some bacteria essentially shut themselves down temporarily when certain antibiotics are present, meaning they don’t metabolize the drug and can reawaken once it’s out of the patient’s system. The nanoparticles keep the bacteria from shutting down, allowing the existing antibiotics to do their jobs, at least in petri dishes.
The U.S. health care system was making some progress on reducing deaths from resistant bacteria before the pandemic, according to a 2019 report from the CDC. It estimated deaths had fallen about 18% since 2013, though that’s based on less-than-precise data.
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