Brigham researchers studying how and why certain cell types proliferate in the gut found that xanthine, which is found in coffee, tea and chocolate, may play a role in Th17 differentiation Insights may help investigators better understand gut health and the development of conditions such as infla
Gut health refers to the overall well-being of the digestive system, including the stomach and intestines. A healthy gut is essential for the proper absorption of nutrients, the elimination of waste, and the maintenance of a balanced microbiome.
The human gut is inhabited by a diverse community of microbes that play a crucial role in both health and illness. Certain microorganisms are believed to be involved in the onset of inflammatory disorders, such as IBD, however, the exact process linking these microbes to the activation of the immune system and the eventual development of the disease is still not fully understood.
“Sometimes in research, we make these serendipitous discoveries—it’s not necessarily something you sought out, but it’s an interesting finding that opens up further areas of inquiry,” said senior author Richard Blumberg, MD, of the Division of Gastroenterology, Hepatology and Endoscopy in the Department of Medicine.
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