Experts are marveling at how U.S. disease detectives figured out how eyedrops were linked to dozens of infections.
This scanning electron microscope image made available by the Centers for Disease Control and Prevention shows rod-shaped Pseudomonas aeruginosa bacteria. The patients’ eyes were painfully inflamed. They could sense light but could see almost nothing else. A doctor called one case the worst eye infection he’d ever seen.
But scientists also shudder, because they have long worried common bacteria will evolve so that antibiotics no longer work against them. The hospital that reported the first infection determined it was caused by a bacteria called Pseudomonas aeruginosa. The institution, which was equipped to do advanced genetic testing, quickly realized the bacteria had a rare gene that protected it from the effects of commonly used antibiotics.
But the California infections were in patients’ eyes, not more common spots like the blood and lungs. Also, the lab analysis determined the infections were caused by a Pseudomonas germ that could resist just about every antibiotic.Over the summer, Pseudomonas outbreaks were seen at long-term care facilities in two other states.
But that suspicion faded in early October, when genetic testing showed the clusters in California, Connecticut and Utah were all caused by the same bacteria strain — a version of the germ that hadn’t been seen anywhere before. In early November, investigators determined most of the infected Connecticut patients had been given artificial tears, though it wasn’t clear who had been given which brand.
In early February, CDC officials issued a public health alert and the FDA recalled the EzriCare eyedrops and Delsam Pharma’s Artificial Tears, another product made by Global Pharma. Last week, the recall was expanded to include Delsam Pharma’s Artificial Eye Ointment.A month before the first recall, the FDA blocked imports of Global Pharma products.
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