A study published in BMCPsychiatry finds that prevalence of liver steatosis and fibrosis is high in Chinese psychiatric patients. Those with antipsychotic polypharmacy and obesity are at high risk and may benefit from early liver assessment.
Raised triglycerides: >150 mg/dL or specific treatment for this lipid abnormality.Table 1 Comparison of glycolipid metabolism in general population and psychopathsWe described the use of medication in 669 psychiatric patients, 85.2% of whom were schizophrenic. As shown in Fig.
, Most patients received 5-hydroxytryptamine-dopamine receptor antagonists alone, followed by phenothiazines and benzamides , and nearly one in five patients received two kinds of 5-HT-D receptor antagonists. Therefore, 5-HT-D receptor antagonists were the main drugs in patients with schizophrenia.
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BMC 257 AMP AL TWOSwitzerland's BMC (Bicycle Manufacturing Company) are based in Switzerland and naturally look to bring the Swiss reputation for precision engineering and quality to the world of e-bikes. In this case that means their 257 AMP AL Two e-bike, an extremely stylish looking commuter that boasts a mouth-watering combinaton of a powerful Bosch mid-drive motor, sizeable battery, powerful lights, superstrong mudguards with integrated rear rack and a sophisticated Kiox display.
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Changes in high-density lipoprotein cholesterol with risk of Cardiovascular Disease among initially high-density lipoprotein-high participants - Cardiovascular DiabetologyBackground High-density lipoprotein cholesterol’s (HDL-C) long-held status as a cardiovascular disease (CVD) preventative has been called into question. Most of the evidence, however, focused on either the risk of death from CVD, or on single time point level of HDL-C. This study aimed to determine the association between changes in HDL-C levels and incident CVD in individuals with high baseline HDL-C levels (≥ 60 mg/dL). Methods 77,134 people from the Korea National Health Insurance Service-Health Screening Cohort were followed for 517,515 person-years. Cox proportional hazards regression was used to evaluate the association between change in HDL-C levels and the risk of incident CVD. All participants were followed up until 31 December 2019, CVD, or death. Results Participants with the greatest increase in their HDL-C levels had higher risks of CVD (adjusted hazard ratio [aHR], 1.15; 95% confidence interval [CI], 1.05–1.25) and CHD (aHR 1.27, CI 1.11–1.46) after adjusting for age, sex, household income, body mass index, hypertension, diabetes mellitus, dyslipidemia, smoking, alcohol consumption, moderate-to-vigorous physical activity, Charlson comorbidity index, and total cholesterol than those with the lowest increase in HDL-C levels. Such association remained significant even among participants with decreased low-density lipoprotein cholesterol (LDL-C) levels for CHD (aHR 1.26, CI 1.03–1.53). Conclusions In people with already high HDL-C levels, additional increases in HDL-C levels may be associated with an increased risk of CVD. This finding held true irrespective of the change in their LDL-C levels. Increasing HDL-C levels may lead to unintentionally elevated risk of CVD.
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The other Chinese apps taking the US and UK by stormFour out of the top 10 most downloaded free mobile apps in the US and UK are Chinese-owned.
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High Supply Lowers Prices, Profits in Mass. Cannabis MarketThe price consumers pay for legal cannabis in Massachusetts is at a five-year low, according to state data. While that is a short-term win for users, it’s bad news over the long term for businesses. The trouble is on two fronts: The wholesale value of the crop is greatly diminished, and at the retail level, businesses must sell about twice…
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