Another new study suggests low serotonin might not be the cause of depression – and it turns out medical experts knew all along.
, starts in style, “…who seems to have little understanding or belief in neuroscience, has gotten a tremendous amount of press out of a non-story.” Neuroscientist Gitte Moos Knudsen, meanwhile, tells me that Moncrieff is “flogging a dead horse”. Considering, though, most of us still think the chemical imbalance thing is legit, Horowitz has a point when he says that “it reflects how poorly the experts have communicated it to the public.
So if it’s not low serotonin, what is it? Given the all-encompassing nature of depression, many variables and theories are being investigated. For Moncrieff herself, it’s purely situational: “There are indeed many theories of other biological mechanisms that might produce depression, but none have been proven or demonstrated consistently,” she says. Here is where it turns contentious: “We do not need to think of depression as a brain disease.
Both see this as a positive thing, something that frees you from concern about having a broken brain. Horowitz, who has been tapering off antidepressants after 20 years of use, notes that this perspective changed him from thinking he was a “fragile person with depression” to looking into past trauma, arguing that the"chemical imbalance story makes people more pessimistic about recovery" and"less likely to choose therapy".
Whichever the case; if low serotonin doesn’t necessarily mean we get depressed, what’s the implication for the seven million people in the UK, like me, onantidepressants work, they’re working; aside from the fact that people are continuing to take them, aseemed to prove they were effective .
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