Harvard scientists developed a new AI tool called CHARM to solve the challenge of real-time DNA decoding of brain tumors during surgery.
"Our tool overcomes this challenge by extracting thus-far untapped biomedical signals from frozen pathology slides."
The current standard intraoperative diagnostic method requires freezing brain tissue and examining it under a microscope. However, freezing can distort cell appearance and impact clinical evaluation accuracy. CHARM also accurately captured visual characteristics, spotting regions with higher cellular density and increased cell death, indicating aggressive glioma types.
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