Scientists test new way to treat eczema SciReports
We used saline as a control representing a vehicle for all the NTCI peptide used in this study. This vehicle control is used in FDA-approved clinical studies of human subjects in which the tested new drug is administered, including therapeutic peptides. Each experiment was performed twice to assure statistical significance and experimental reproducibility.
The Treatment Protocol : the initiation of AD-like phenotype induction began with a bolus dose of 6 nmoles MC903 applied topically to the right ear . Repeated exposure to the irritant was initiated on day 3 with 2 nmoles of MC903 and the challenge was continued for 21 days. NTCI treatment was introduced on day 20 as a twice daily topical application of its saline solution and was continued for 9 days. The control group of mice received a topical saline treatment on both sides of the right ear.
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