First transfusions of lab-grown blood Blood Anemia Bleeding Genetic RedBloodCells StemCells Transplant BloodTransfusion
By Benedette Cuffari, M.Sc.Nov 9 2022Reviewed by Aimee Molineux Recently, two patients in the United Kingdom received two small doses of lab-grown blood samples as part of the RESTORE trial.About the RESTORE trial The RESTORE trial is a single-center, randomized, controlled, phase I cross-over trial that is a joint effort between the National Health Service Blood and Transplant and the University of Bristol.
Once isolated, the stem cells were then placed in a nutrient solution that supports their development into mature RBCs. After about three weeks of being incubated within this solution, the newly formed RBCs were purified and tagged with a radioactive substance that allows the scientists to monitor the lifespan of the cells within the recipients’ bodies.
Genetics & Genomics eBook Compilation of the top interviews, articles, and news in the last year. Download a copy today Although further studies will be needed to assess the efficacy of lab-grown RBCs as a substitute for conventional RBCs in treating different health conditions, the RESTORE trial will provide important information on the safety of these manufactured cells to support additional research in the future.
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