Drug and non-drug therapies for HFpEF, the search for AF, and exercise as medicine are the topics drjohnm, discusses in this week’s podcast.
EF , the drugs are beneficial, but I find the results in HFpEF underwhelming. I’d be less worried about it if the drugs were not so costly.
For DELIVER, you had to have an EF ≥ 40% to be enrolled. But the mean EF was far greater than that. The mean LVEF was 54%. Only about one-third of patients had EFs between 40% and 49%. That’s a lot higher than in the HFrEF trials. These are different patients.
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