FDA Advisers Say Next Round of COVID Booster Shots Should Target an XBB Variant

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FDA Advisers Say Next Round of COVID Booster Shots Should Target an XBB Variant
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COVID booster shots for the fall should be updated to protect solely against one of the three XBB variants that have taken hold in the US.

during a time when the virus has further evolved, immunity of the population has waned further, and we move indoors for wintertime,” he told the panel, theA big question will be who should get the updated boosters, Dr. Paul Offit, a vaccine scientist at the Children's Hospital of Philadelphia and a member of the advisory committee, told“What's the goal of the vaccine?” he asked.

FDA scientists believe redesigned boosters should target at least one variant of XBB, according to briefing documents published Monday.to more closely match currently circulating Omicron sublineages is warranted for the 2023-2024 vaccination campaign,” the scientists wrote. The World Health Organization and the European Medicines Agency have both already said that a booster should target an XBB subvariant.have evolved, from a shot in December 2020 that targeted the original virus to FDA-approved shots last fall that targeted the original COVID strain as well as the Omicron subvariants BA.4 and BA.5.

XBB 1.5 is the dominant strain now circulating, with 40% of new cases having this strain, according to the CDC. About 18% of new cases have XBB.1.16 and 12.5% have XBB 1.9.1.The FDA's Advisory Committee on Immunization Practices, which will decide who should get a booster, will also meet next week to talk about this and otherIt would make sense if the COVID boosters were offered to everyone in the fall, Dr.

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