The scientific quest for a universal coronavirus vaccine received a boost Wednesday.
The new paper isn’t the first instance in which Fauci has mentioned the importance of
Sequencing the genomes of such viruses could help researchers identify new threats and discover commonalities between coronaviruses that a new vaccine could then target. Testing universal vaccines in human challenge studies will be important, too, the authors argue. That type of research could accelerate vaccine development, but it’s ethically complicated because it involves intentionally infecting people to test a vaccine.
“You have people going into the caves where bats are. You don’t want spillovers,” Penaloza-MacMaster said. Penaloza-MacMaster’s lab is working on a vaccine that targets proteins “at the guts of the virus,” he said, while other labs are evaluating a nanoparticle vaccine, which features multiple spike proteins from different viruses.
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