Engineered stem cell therapy presents a promising therapeutic strategy for a highly malignant brain tumor, says US scientist.
"Our focus is on how we use stem cells and cancer cells from humans to treat cancer," said Dr. Shah, vice chair of research at Brigham and Women's Hospital Neurosurgery."Recently, we also used a patient's own tumor cells, gene-engineered them, to treat the patient's cancer. In a nutshell, we play with cells, repurpose them and use them for cancer therapy," said Dr.
"Time has remained static for GBM," said Dr. Shah, adding, "One of the reasons is that it is a very aggressive tumor and to deliver drugs to the brain is extremely difficult."One of the ways to treat or potentially cure cancers is with a treatment that can be developed and delivered locally, he said, adding, "one of the best options is to use viruses or cells that can deliver therapeutics locally.
They discovered that encapsulating the therapeutic cells in biodegradable hydrogel prevented them from being washed away by cerebrospinal fluid and had the best therapeutic efficacy in murine models. "In the future, we will be applying this strategy to identify target receptors promptly after [patients] receive a GBM diagnosis," he said.
The CRISPR system uses the same mechanism which enables bacteria to recognize genetic sequences of invaders and target these sequences for destruction using specialized enzymes. These enzymes are called CRISPR-associated proteins and include the DNA endonuclease Cas9."We gene-edited tumor cells using CRISPR.
"The pill culture is going to end at some point because we are using pills as band-aids, but it doesn't fix the disease," Shah added.
Österreich Neuesten Nachrichten, Österreich Schlagzeilen
Similar News:Sie können auch ähnliche Nachrichten wie diese lesen, die wir aus anderen Nachrichtenquellen gesammelt haben.
Morgan Stanley Analyst Says Crypto Economy's Liquidity Improved, but There's 'No Huge Demand to Re-Leverage' – Market Updates Bitcoin NewsMorgan Stanley’s Sheena Shah highlighted that the stablecoin market cap is seeing fewer redemptions for the first time since April. CryptoEconomy CryptoWinter
Weiterlesen »
Old news clipping helps cancer patient prove he was at WTC on 9/11, collect benefitsAn old newspaper clipping from across the country helped a cancer patient prove he was at the World Trade Center on 9/11.
Weiterlesen »
'The Sandman' Is Almost Too Faithful to Its Source MaterialThe potential of The Sandman is visible in almost every frame; the trick is how to turn that dream into reality.
Weiterlesen »
Opinion: Army Corps should not value a vacation rental more than a family’s homeThe U.S. Army Corps of Engineers relies on a benefit-cost analysis to advance projects...
Weiterlesen »
Health Canada recalls medication that could provoke overdoseHydromorphone is an opioid used to treat pain and troubles linked to the consumption of opioids.
Weiterlesen »
Should It Be Easier to Take Away a Driver’s License?A driver’s license can be taken away if you break the law too many times, but in reality, this system is designed to fail in places that all but require the use of a car. awalkerinLA reports on how we often treat a license like a right, not a privilege
Weiterlesen »