Younger women suffering from a common form of advanced breast cancer have experienced significantly improved survival rates when treated with a drug that targets cancer cells, according to the findings of an international clinical trial
The study was conducted among 672 women under the age of 59 who received a drug called ribociclib, in combination with a common form of hormone therapy. Seventy percent of the women who took the combination therapy were alive after 42 months according to the findings, compared to 46% for women who were treated with only the hormone therapy and a placebo.This, the researchers said, corresponded to a 29% lower risk of death in patients receiving the combination therapy.
"This study confirms the benefits of these drugs are similar in both pre- and post-menopausal patients with advanced hormone receptor-positive breast cancers, and it further validates the clinical value of adding ribociclib for these patients," said study co-author Dr. Debu Tripathy from the University of Texas MD Anderson Cancer Center.The most common adverse reaction to the drug was a lowered white blood cell count, which can lead to infections.
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