A pig kidney successfully functioned in a human body for about two months, marking the longest documented case of a xenotransplant of its kind.
“None of this would have been possible without the incredible support we received from the family of our deceased recipient. Thanks to them, we have gained critical insight into xenotransplantation as a hopeful solution to the national organ shortage,” he added.The team will now conduct an in-depth study to analyze the experiment results.
The kidney was procured from a GalSafeTM pig for the experiment, approved by the Food and Drug Administration in December 2020. Its applications include human therapeutics and as a dietary source for those suffering from alpha-gal syndrome, a meat allergy caused by a tick bite,The team genetically modified and engineered the pig’s organ so the human body wouldn’t reject it.
“To create a sustainable unlimited supply of organs, we need to know how to manage pig organs transplanted into humans,” said Dr. Montgomery. “Testing them in a decedent allows us to optimize the immunosuppression regimen and choice of gene edits without putting a living patient at risk.”
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