Uncle is a never-seen-before solution, allowing ultra-efficient biologics stability screenings
Users can use Uncle to obtain insights through protein stability assessments, accommodating up to 48 samples in less than two hours when exploring novel formulations or constructs. Simultaneously, it is possible to determine T, gaining a clear understanding of when unfolding triggers aggregation. Users can also incorporate a DLS read before the temperature ramp to identify potential aggregation issues immediately.
With Uncle's convenient out-of-the-box isothermal applications, users can effortlessly load their samples into Unis, incubate them, and later return them to Uncle for analysis to identify any anomalies, leaving Uncle available for other tasks.Before the AAV capsid pops, Uncle teams up with SYBR Gold to predict when the DNA leaks and calculate the initial amount of free DNA and the remaining amount after a thermal ramp.
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