A modular and customizable synthetic receptor for use in immunotherapy.
A promising tool in the fight against cancer is CAR T therapy, in which immune cells called T cells are engineered to express a synthetic receptor protein, the chimeric antigen receptor , on their surface.
CAR proteins recognize an extracellular target — an antigen molecule from a nearby tumour cell — and stimulate the T cell to trigger an immune cascade in response. However, the widespread application of this emerging therapy in tumours is limited by the lack of truly tumour-specific antigens, which often leads to unwanted side effects in healthy tissues. The design of synthetic-protein circuits that prevent CAR T cells from being activated outside tumours could reconcile potency with safety.
Österreich Neuesten Nachrichten, Österreich Schlagzeilen
Similar News:Sie können auch ähnliche Nachrichten wie diese lesen, die wir aus anderen Nachrichtenquellen gesammelt haben.
How the Kremlin Infiltrated Russia’s FacebookVKontakte was created to empower free speech, but it has instead enabled government censorship and arrests.
Weiterlesen »
Zendaya Is the Picture of Pure Opulence in Bulgari’s New CampaignTracking all of the latest designer drops and capsule collections of the season.
Weiterlesen »
Botter, Peter Do and Ottolinger Among Andam 2022 FinalistsThe prestigious awards offer young designers an opportunity to present their collections in Paris.
Weiterlesen »
This Nintendo Switch Carrying Case Has Over 50K 5-Star Reviews — & Is Under $15This top-rated case keeps your gamer's favorite console at their fingertips ... and safe from damage.
Weiterlesen »
Mobile Banking: 5 Rules of Safety You Should Know | HackerNoonHow safe it is to use mobile applications and web versions of banks to make payments?
Weiterlesen »