Depressive symptoms are associated with fatigue, poorer functional status and less engagement in sports in axSpA and PsA: an analysis from the RABBIT-SpA cohort - Arthritis Research & Therapy

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Depressive symptoms are associated with fatigue, poorer functional status and less engagement in sports in axSpA and PsA: an analysis from the RABBIT-SpA cohort - Arthritis Research & Therapy
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A study in Arthritis Research & Therapy finds that in patients with axial spondyloarthritis or psoriatic arthritis, depressive symptoms are common and mostly associated with fatigue, not engaging in sports, and limited physical function.

]. Sex, disease duration , obesity , arthritis vs. no), and enthesitis vs. no) were physician reported. Data on comorbidities was also collected from the rheumatologist, using a checklist of comorbidities relevant to axSpA and PsA, including for example cardiovascular diseases but also depression. The checked comorbidities were counted and the result categorized . Education and engaging in sports were collected in the patient CRF.

To identify sociodemographic or clinical factors that are associated with depressive symptoms, moderate and severe depressive symptoms were combined and compared to patients with no or mild depressive symptoms. For these two groups, a multivariate logistic regression was used to determine associations between independent variables and depressive symptoms. Adjusted odds ratios are given with 95% confidence intervals .Calculations were carried out with the software package SAS, version 9.

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