A person's previous COVID19 infections will determine their body's immune response to future variants, according to new research
Antibody levels wane over time following infection or vaccination, but this new research shows that an individual's protective immune responses are also affected by which strain or combination of strains they have been exposed to.
Professor Danny Altmann, from Imperial's Department of Immunology and Inflammation, said:"We've recently had some very large studies making the point that vaccine immunity wanes quite rapidly. "This leaves us vulnerable to Delta breakthroughs, and protection can generally be rescued by a third dose."You can be someone who made a great response to the vaccine and still fall prey to Delta breakthrough if you haven't had a booster."
He added:"The really surprising news was finding that people infected with the Alpha variant had such different patterns and waning of immunity to other variants. "Immune imprinting means we're now all walking around programmed slightly differently for our future protection."strain and the scientists involved in the study stressed there was still insufficient data on the new variant of concern to draw any conclusions.
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