By setting their sights on dogs, longevity researchers hope to discover ways to turn back time in humans
Stephanie Abraham, a dog breeder and dog-show judge in Connecticut, lives with eight laid-back Cavalier King Charles Spaniels and a mischievous one named Ace. “He’s my only Cavalier who gets into trouble!” she says. The nine-year-old 18-pounder, with rich chestnut-color markings and large, soulful eyes, likes to leap on a kitchen chair, swipe mail off the butcher-block counter, and munch it to shreds. “The latest thing he chewed was my summons for jury duty,” Abraham says.
“We view the world like this—we think aging is reversible,” says Daniel Oliver, co-founder and CEO of Rejuvenate Bio, the gene therapy’s developer. “If you are able to affect aging, you should be able to affect multiple age-related conditions.” Even if experiments in dogs yield nothing to thwart human aging, they may produce novel treatments for our furry friends—and nobody who has ever bid farewell to a cherished canine would object to that. “If we solve the problem of longevity with dogs, we will reduce lots of grieving and suffering,” says molecular biologist and cancer researcher Andrei Gudkov, who co-founded an organization that’s studying aging in retired sled dogs. He named it Vaika, after his late Siberian Husky.
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