A new and very prevalent kind of prostate cancer A recent study by a group of researchers at Memorial Sloan Kettering Cancer Center (MSK) and Weill Cornell Medicine finds that a previously unidentified subtype of hormone-resistant prostate cancer makes up roughly 30% of all cases. The study was rec
The researchers believe that the findings could make it possible for those with this kind of prostate cancer to get targeted treatments.A recent study by a group of researchers at Memorial Sloan Kettering Cancer Center and
Dr. Chen and his colleagues looked at 40 distinct patient-derived models of prostate cancer that were gathered from patients who had cancer treatment at MSK and Weill Cornell to make their discovery. “Prostate cancer is uniquely difficult to propagate in the lab,” Dr. Chen explains. “Whereas there are hundreds of cell lines of melanoma and lung cancer, there’s only three or four prostate cancer cell lines that are useful.”
They could then determine whether genes are activated or inactive in the cells using these patient-derived organoids as a starting point. The scientists utilized this data to establish the existence of a new subtype of prostate cancer. “Once patients become resistant to antigen deprivation,” he continues, “it becomes a universally lethal disease.”
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