The outbreak sickened hundreds of young children worldwide last year
There were at least 35 known cases of unexplained acute paediatric hepatitis among children in Scotland last year. Most had been previously healthy, and one required a liver transplant
All were diagnosed with acute hepatitis - a severe and potentially deadly inflammation of the liver - but there was no obvious cause. The researchers were able to confirm the presence of AAV2 in the liver of all the patients who were ill with acute hepatitis. A version of AAV is currently used as a vector in gene therapies, including haemophilia treatment, and hepatitis is a common side-effect.
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