The study finds that COVID-19 vaccination can significantly reduce symptoms and improve well-being in patients suffering from post-COVID-19 conditions (PCC). Vaccination also lowered systemic markers of inflammation but did not entirely eliminate persistent SARS-CoV-2 antigens, which may continue to contribute to inflammation.
By Neha MathurSep 22 2023Reviewed by Susha Cheriyedath, M.Sc. In a recent article published in the International Journal of Infectious Diseases, researchers evaluated a cohort of post-COVID-19 conditions patients before and after coronavirus disease 2019 vaccination to determine its potential role in PCC management.
Clinically, PCC is heterogeneous, with over 200 symptoms, but its precise underpinnings remain unclear. The World Health Organization defines PCC as the persistence of symptoms beyond 12 weeks from diagnosis for at least two months. Studies have demonstrated that vaccination, received before or after acute SARS-CoV-2 infection, protects against severe COVID-19. However, there is a lack of evidence that COVID-19 vaccines confer protective and therapeutic effects on PCC.
The study cohort comprised 83 individuals infected with SARS-CoV-2 and diagnosed with PCC per the WHO PCC case definition. Of these, 44 had not received a COVID-19 vaccine at baseline , while 39 had received one to two vaccine doses. Furthermore, the team quantified soluble SARS-CoV-2 spike and nucleocapsid proteins and immunoglobulins G and IgM levels elicited in response to these antigens.
Although inflammation impaired the immunocompetence of PCC patients, post-PCC vaccination promoted anti-S IgG responses, which likely lowered persistent viral burden and reduced autoantibody titers.
Österreich Neuesten Nachrichten, Österreich Schlagzeilen
Similar News:Sie können auch ähnliche Nachrichten wie diese lesen, die wir aus anderen Nachrichtenquellen gesammelt haben.
PCC to ask for public views on police station ‘front counters’Walking-in to see a police officer at a ‘front counter’ is no longer an option at most police stations.
Weiterlesen »
Rehabilitation interventions aid post-COVID-19 condition: StudyStandardized rehabilitation interventions are associated with improvements in functional exercise capacity in patients with post-COVID-19 condition (PCC), according to a review published online Sept. 19 in JAMA Network Open.
Weiterlesen »
Early treatment with convalescent plasma may reduce risk of long COVIDFindings from a nationwide, multicenter study led by Johns Hopkins Medicine and the Johns Hopkins Bloomberg School of Public Health suggest that patients with COVID-19 have less chance of developing post-COVID conditions -; commonly known as long COVID -; if they receive early treatment with plasma from convalescent (recovered) COVID patients that contain antibodies against SARS-CoV-2, the virus that causes COVID-19.
Weiterlesen »
Study identifies a molecule that may be behind COVID-19 brain fogA study identifies a molecule that may be behind cognitive symptoms, including 'brain fog,' experienced by those infected by the SARS-CoV-2 virus.
Weiterlesen »
Repeated vaccine doses protect elderly against COVID-19, Swedish study showsMore and more frequent vaccine doses than in other countries reduce mortality in COVID-19 in nursing homes. This is shown by a Swedish study, led by Anders Johansson and Mattias Forsell, Umeå University, which was published in The Lancet Infectious Diseases.
Weiterlesen »
Worldwide study investigates emotional experiences and psychological well-being during the COVID-19 pandemicPeriods of collective stress, such as a pandemic or climate crisis, have a major impact on our psychological well-being. What role do emotions play in helping us cope during tough times? In a worldwide study by sixty-two scientists among more than 24,000 participants in fifty-one countries, a relationship was established for the first time between specific emotions and well-being during a period of collective stress.
Weiterlesen »