Blood substitute repairs damaged organs hours after heart stops

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Blood substitute repairs damaged organs hours after heart stops
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A procedure that reverses cell damage after the heart has stopped pumping blood may lead to more organ transplants and better treatments for heart attacks and strokes, and one day could even rescue people who would currently be considered dead

Kidney tissue from a pig after OrganEx treatment. The green stain shows cytoskeletal beta-actin, which appears more dimly if the cell is damagedA procedure that reverses cell damage after the heart has stopped pumping blood may lead to more organ transplants and better treatments for heart attacks and strokes, and one day could even save the lives of people who would currently be considered dead.

But if someone’s heart stops while they are outside of a hospital, their cells and organs are quickly damaged by the lack of oxygen and their chances of survival plummet. Their blood becomes more acidic from a build-up of CO2 and many damaging substances are released.

In 2019, Vrselja and his team reported that their system could reverse signs of cell death when connected to the brains of pigs,. In the latest study, they wanted to see if the fluid could help reverse the damage that occurs in other organs after death, and to test it in whole bodies.

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