Baricitinib, a drug commonly used by people with rheumatoid arthritis, reduced hospitalized COVID19 patients’ risk of dying by 13% when taken with other proven COVID-19 drugs.
. Now, baricitinib reduces deaths even further. “This is a drug that is just as effective as tocilizumab,” Landray says. “The effect size is very similar.”
But the rise of the Omicron variant of SARS-CoV-2 has also challenged progress in treating COVID-19. Several antibody treatments are ineffective against this variant, which now dominates infections across the globe. In its recent guideline update, WHO recommended that an antibody cocktail, casirivimab-imdevimab, only be given when a different variant has caused an infection.
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