With returns from antibiotics down, big pharmaceutical companies have abandoned them for more lucrative drugs
of penicillin in 1943 was a lottery in America. The “miracle drug” had been discovered 15 years earlier but production capacity was limited, and most went to the war effort. What remained was rationed, and a single injection cost at least $40 . By 1949 better manufacturing methods allowed the price to fall to 20 cents. The use of penicillin exploded.
The demise of Achaogen has been blamed on the peculiar features of the antibiotics market, rather than the poor business decisions of its managers. The low number of cases that are suitable for potential treatment with novel antibiotics makes it hard to recruit enough patients for clinical trials. Take carbapenem-resistant, which Achaogen went after. These bacteria kill half of those whose bloodstream they infect.
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