Treatments for non-small-cell lung cancer aren't what they used to be -- learn more about advances in targeted therapies:
Non-small-cell lung cancer is a very prevalent disease. But disease rates have gone down -- and hopefully will continue to go down -- over time. This is in part because of preventive measures: Fewer people are smoking cigarettes. Although there are many people who have lung cancer who have never been smokers, cigarette smoking is far and away the leading cause of lung cancer.To understand where NSCLC treatment is headed, it helps to understand where it is now.
For people whose disease has spread beyond the lung to involve a regional, or close-by, area, treatment is a bit more complicated. But we still approach it with the intent to cure. We may use a mix of surgery, radiation, chemotherapy, and immunotherapy. In people with metastatic disease, where the cancer has spread outside the chest, local therapies aren’t effective. Then we look at others that will work throughout the entire body.
Before that, researchers weren’t looking to divide a common tumor into groups. But we now recognize that by doing that, we can develop treatments for small groups of people and even some rare mutations. Often there are now multiple different drugs available, even for fairly rare subtypes of lung cancer. Also, the use of immunotherapy has really changed the outlook for people with lung cancer. Some live very healthy lives with a normal lifespan, sometimes even with no further therapy.
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