A study finds that deep brain stimulation to areas of the brain associated with reward and motivation could be used as a potential treatment for depression. According to researchers at the University of Texas Health Science Center at Houston, deep brain stimulation (DBS) to the superolateral bran
The National Institutes of Health estimate that in 2020, approximately 21.0 million individuals had at least one major depressive episode in the United States.
DBS has long been used to treat people with movement disorders including Parkinson’s disease, tremors, and dystonia, and it has also been investigated as a potential therapy for those with treatment-resistant depression. DBS involves implanting electrodes into specific brain areas, where they produce electrical impulses that change brain activity.
“We targeted a bundle of fibers that leave this small area in the brainstem to travel to other areas throughout the brain,” Conner said. “The PET scans indicated that this small target area has very diffuse downstream effects. It’s not one single effect because there’s not one single area of the brain linked to depression. The whole brain needs to be changed and through this one small target, that’s what we were able to do.
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