A Nobel prize in physiology for mRNA vaccines

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A Nobel prize in physiology for mRNA vaccines
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Katalin Karikó and Drew Weissman helped pioneer a technology that saved millions of lives

which award the Nobel science prizes are hard to second-guess. Last year, for instance, the physiology prize went toA worthy winner. But some thought the choice an odd one in light of the covid-19 pandemic that had recently ravaged the world. A more obvious set of laureates might have been some of those who helped develop the mvaccines which had been invented, tested and deployed in record time against the virus.

The winners it chose were Katalin Karikó and Drew Weissman, once colleagues at the University of Pennsylvania, in Philadelphia, though Dr Karikó now works mainly at the University of Szeged, in her native Hungary. Many people can claim a stake in the development of mvaccines, but theirs was, perhaps, the critical insight. It was they who worked out how to stop the molecule at the heart of such vaccines provoking a reaction which would otherwise have made them unusable.

All this happened way back in 2005. As is the way of things, matters then developed slowly but steadily. By early 2020, when the world’s governments hit the panic button, two firms—Biovaccines. They were able to switch their attention and develop versions effective against the newly discovered coronavirus. They did this by causing the mBillions of jabs and millions of lives later, Dr Karikó and Dr Weissman were heroes.

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